The Inquisition moves amongst mankind like an avenging shadow, striking down the enemies of humanity with uncompromising ruthlessness. When he finally corners an old foe, Inquisitor Gregor Eisenhorn is drawn into a sinister conspiracy. As events unfold and he gathers allies - and enemies - Eisenhorn faces a vast interstellar cabal and the dark power of daemons, all racing to recover an arcane text of abominable power: an ancient tome known as the Necroteuch.

For a thousand years, the Sabbat Worlds have been lost to the Imperium, claimed by the dread powers of Chaos. Now, a mighty crusade seeks to return the sector to Imperial rule. And at the forefront of that crusade are Colonel-Commissar Ibram Gaunt and the Tanith First and Only - better known as Gaunt’s Ghosts. Trapped in the grinding trench warfare of Fortis Binary, the Ghosts find themselves drawn into a conspiracy to assassinate the crusade’s leader, Warmaster Macaroth.

When his body is hideously damaged in an enemy attack, it looks as though Inquisitor Gideon Ravenor's promising career would be abruptly brought short. Now, encased in a life support sytem that keeps him alive but forever cuts him off from the physical world, Ravenor utilises his formidable mental powers to continue his investigations. Along with his retinue of warriors and assassins, Gideon Ravenor fights to protect an Imperium he can no longer see, hear or feel.

On Monthax, Colonel-Commissar Ibram Gaunt and his Tanith First-and-Only await the order to advance into the sweltering jungle and drive the alien eldar from the world. As battle approaches, Gaunt walks the lines, raising his men's spirits and remembering their most heroic deeds - and the tragedies that have dogged Gaunt's Ghosts from the day of their founding on lost Tanith. The day that Gaunt became known as the Ghostmaker.

Two centuries ago, the Imperium of Man and the upstart Tau Empire fought to a standstill in the Damocles Gulf. Now, as the 41st millennium draws to a close, the tau have returned. As the world of Agrellan falls under attack, the White Scars and Raven Guard rush to its defence, but with the skilled Commander Shadowsun leading the alien forces, the Space Marines and their allies are hard pressed. Kor'sarro Khan, Huntmaster of the White Scars, swears that he will win the day in the most direct way possible – by taking Shadowsun's head.