Connie Byrne, a nurse in London's East End working alongside Millie Sullivan from Call Nurse Millie, is planning her wedding to Charlie Ross, set to take place as soon as he returns from the war. But when she meets him off the train at London Bridge, she finds that his homecoming isn't going to go according to plan.
Connie's busy professional life, and the larger-than-life patients in the district, offer a welcome distraction, but for how long?