Genetic History

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. 

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.

In his provocative new book, evolutionary biologist Jerry A. Coyne lays out in clear, dispassionate detail why the toolkit of science, based on reason and empirical study, is reliable, while that of religion - including faith, dogma, and revelation - leads to incorrect, untestable, or conflicting conclusions.

We are capable of savage acts of violence but also spectacular feats of kindness: is one side of our nature destined to win out over the other? Every act of human behaviour has multiple layers of causation, spiralling back seconds, minutes, hours, days, months, years, even centuries, right back to the dawn of time and the origins of our species. In the epic sweep of history, how does our biology affect the arc of war and peace, justice and persecution? How have our brains evolved alongside our cultures?

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

Resistance to malaria. Blue eyes. Lactose tolerance. What do all of these traits have in common? Every one of them has emerged in the last 10,000 years.

How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean B. Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions.

Among the estimated 100 billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of "becoming" in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. 

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

A Pocket History of Human Evolution brings us up-to-date on the exploits of all our ancient relatives. Paleoanthropologist Silvana Condemi and science journalist François Savatier consider what accelerated our evolution: Was it tools, our "large" brains, language, empathy, or something else entirely? And why are we the sole survivors among many early bipedal humans? Their conclusions reveal the various ways ancient humans live on today - from gossip as modern "grooming" to our gendered division of labor - and what the future might hold for our strange and unique species. 

Evolution is one of the most important processes in life. It not only explains the detailed history of life on earth, but its scope also extends into many aspects of our own contemporary behavior - who we are and how we got to be here, our psychology, our cultures - and greatly impacts modern advancements in medicine and conservation biology. Perhaps its most important claim for science is its ability to provide an overarching framework that integrates the many life sciences into a single unified whole. Yet, evolution has been, and continues to be, regarded with suspicion by many.

 DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction. 

 Brains Through Time examines how vertebrate nervous systems evolved in conjunction with other organ systems and the planet's ecology. Surveying an enormous range of information on genes and proteins, sensory and motor systems, central neural circuits, physiology, and animal behavior, the authors reconstruct the major changes that occurred as vertebrates emerged and then diversified. 

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

On the Origin of Species is one of the most important and influential books of its time and remains one of the most significant contributions to philosophical and scientific thought. The theories Darwin sets out here had an immediate and profound impact on the literature and philosophical thought of his contemporaries and continue to provoke thought and debate today. Written for the general public of the 1850s, On the Origin of Species laid out an evolutionary view of the world which challenged contemporary beliefs about divine providence and the fixity of species.

The Big Ratchet is the story of the ratchets: the technologies and innovations, big and small, that propelled our species from hunters and gatherers on the savannahs of Africa to shoppers in the aisles of the supermarket. Our species long lived on the edge of starvation. Now we produce enough food for all 7 billion of us to eat nearly 3,000 calories every day. This is such an astonishing thing in the history of life as to verge on the miraculous. The Big Ratchet is the story of how it happened.

Richard Dawkins, author of The God Delusion and a life-long committed Darwinist, abridges and reads this special audio version of Charles Darwin's famous book. A literally world-changing book, Darwin put forward the anti-religious and scientific idea that humans in fact evolved over millions of generations from animals, starting with fish, all the way up through the ranks to apes, then to our current form.