Medical Genetics

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

Henry and Nomi are thrilled to find out they’re going to be parents. There is so much to think about, so many decisions they’ll need to make, about feeding schedules and childcare and schools. But there’s one decision they never would have imagined facing, and even considering the choice is a minefield of emotions and experiences and expectations. After all, the only thing that hangs in the balance is the course of their child’s life.

What if you were capable of more? Your concentration was better, you could multitask quicker, read faster, memorize more, sleep deeper. For Logan Ramsay, it’s happening. He’s beginning to see the world around him, even those he loves the most, in whole new ways. He knows that it’s not natural, that his genes have been hacked. He has been targeted for an upgrade.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

Carl Zimmer investigates one of the biggest questions of all: what is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on Earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts - whether a fertilised egg is a living person, for example, and when we ought to declare a person legally dead.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Blue Magic, the latest designer drug linked to a rash of overdoses, might explain the needle mark on the arm of a young woman found dead in her Kansas City apartment. But when star reporter Rich Azadian digs deeper, the clues point to a far more explosive story: MaryLee Stock was a special protege of evangelical megapastor and power broker Cobalt Becker, who is poised to deliver his followers and the presidency to a firebrand right-wing senator in the next election.

Since the dawn of civilization, it's been mankind's greatest dream: immortality and eternal youth. Dramatic advances in medical science have finally made it possible. But in order to preserve everyone's youthful state, they must undergo an irreversible operation before passing into adulthood. A special hormone patch maintains each person's body in the form of a preadolescent 11-year-old.

In the new essays collected here, an interdisciplinary group of scholars asks age-old questions about the nature and well-being of humans in the context of a revolutionary new biotechnology - one that has the potential to change the genetic make-up of both existing people and future generations. Welcoming listeners who study related issues and those not yet familiar with the formal study of bioethics, the authors of these essays open up a conversation about the ethics of gene editing.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

A homeland security agent is found dead. Shocking evidence reveals the cause of death is the simultaneous collapse of the man's blood vessels. When a second body sharing the same gruesome symptoms is found, the hunt is on for a frightening new kind of killer. A vicious assault on his leading genetics researcher puts Dr. Ronni Saar, the CEO of Double N, and his friend Gadi, a former military police investigator, on the trail of a sophisticated killer. The deeper Gadi digs, and the more he learns, the more dangerous the terrain becomes.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

With trusted expertise from Mayo Clinic, the Edge of Medicine series sets out to inspire and educate the next generation of young scientists by highlighting the medical breakthroughs of a diverse range of scientists and researchers. From the discovery of the double helix to mapping the human genome, this exploration of scientific inquiry celebrates the greatest developments to date in genetics. Get to know the physicians, scientists, and other researchers responsible for these breakthroughs in medicine, and explore the ups, the downs, and the eureka moments that are science in action.

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

In 2025 America, it's hardly news when a renowned octogenarian scientist dying of cancer disappears from a local hospice, but when Kansas City Star reporter Rich Azadian begins to dig, he discovers that other elderly scientists around the world have also vanished recently - all terminally ill and receiving the same experimental treatment from a global health company.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

Luke Abramson, a brilliant cellular biologist who is battling lung cancer, has one joy in life: his 10-year-old granddaughter, Angela. When Angela is diagnosed with an inoperable brain tumor and given less than six months to live, Luke wants to try a new enzyme, Mortality Factor 4 (MORF4), that he believes will kill Angela's tumor. However, the hospital bureaucracy won't let him do it because MORF4 has not yet been approved by the FDA. Knowing Angela will die before he can get the treatment approved, Luke abducts her from the hospital with plans to take her to a private research laboratory in Oregon.

Ex-Navy SEAL Nolan Kilkenny receives a desperate plea for help from doctors frantic to save the life of a young boy with a deadly genetic disorder. The boy, who came to his parents through a blind adoption, has no known blood relatives. Nolan agrees to help, but as he is being prepped for surgery, the boy dies. Further genetic testing then reveals an astonishing truth: Nolan and the boy share the same biological father. Nolan must confront his own father to find out the truth behind the discovery, and uncovers a heinous blackmail plot and desperate victims and villains.