Medical Genetics

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

Blue Magic, the latest designer drug linked to a rash of overdoses, might explain the needle mark on the arm of a young woman found dead in her Kansas City apartment. But when star reporter Rich Azadian digs deeper, the clues point to a far more explosive story: MaryLee Stock was a special protege of evangelical megapastor and power broker Cobalt Becker, who is poised to deliver his followers and the presidency to a firebrand right-wing senator in the next election.

Since the dawn of civilization, it's been mankind's greatest dream: immortality and eternal youth. Dramatic advances in medical science have finally made it possible. But in order to preserve everyone's youthful state, they must undergo an irreversible operation before passing into adulthood. A special hormone patch maintains each person's body in the form of a preadolescent 11-year-old.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

Henry and Nomi are thrilled to find out they’re going to be parents. There is so much to think about, so many decisions they’ll need to make, about feeding schedules and childcare and schools. But there’s one decision they never would have imagined facing, and even considering the choice is a minefield of emotions and experiences and expectations. After all, the only thing that hangs in the balance is the course of their child’s life.

Carl Zimmer investigates one of the biggest questions of all: what is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on Earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts - whether a fertilised egg is a living person, for example, and when we ought to declare a person legally dead.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

In the new essays collected here, an interdisciplinary group of scholars asks age-old questions about the nature and well-being of humans in the context of a revolutionary new biotechnology - one that has the potential to change the genetic make-up of both existing people and future generations. Welcoming listeners who study related issues and those not yet familiar with the formal study of bioethics, the authors of these essays open up a conversation about the ethics of gene editing.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

A homeland security agent is found dead. Shocking evidence reveals the cause of death is the simultaneous collapse of the man's blood vessels. When a second body sharing the same gruesome symptoms is found, the hunt is on for a frightening new kind of killer. A vicious assault on his leading genetics researcher puts Dr. Ronni Saar, the CEO of Double N, and his friend Gadi, a former military police investigator, on the trail of a sophisticated killer. The deeper Gadi digs, and the more he learns, the more dangerous the terrain becomes.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

Gabriel Schist is spending his remaining years at Bright New Day, a nursing home. He once won the Nobel Prize for inventing a vaccine for AIDS. But now, he has Alzheimer’s, and his mind is slowly slipping away. When one of the residents comes down with a horrific virus, Gabriel realizes that he is the only one who can find a cure. Encouraged by Victor, an odd stranger, he convinces the administrator to allow him to study the virus. Soon, Gabriel’s hallucinations interfere with his work. Can he find a cure before his brain deteriorates past the point of no return?

Charlotte Raven had never heard of Huntington's disease when, in her mid-30s, she discovered that her father was suffering from the illness. Life for her and her young family would never be the same again. Patient 1 is her brutally candid account of coming to terms with this inherited neurodegenerative disease, which can manifest at any time in life for people who carry the faulty gene.

George Galen is a brilliant scientist, a pioneer in gene therapy. But Galen is dangerously insane. He has created a method to alter human DNA, not just to heal diseases, but also to "improve" people - make them stronger, make them able to heal more quickly...and make them compliant to his will.

In 2025 America, it's hardly news when a renowned octogenarian scientist dying of cancer disappears from a local hospice, but when Kansas City Star reporter Rich Azadian begins to dig, he discovers that other elderly scientists around the world have also vanished recently - all terminally ill and receiving the same experimental treatment from a global health company.

Es ist nichts Geringeres als eine medizinische Sensation: Durch die Entdeckung eines neuen Wundermittels kann der Alterungsprozess des Menschen aufgehalten werden! Wer das Medikament regelmäßig nimmt bleibt nicht nur ewig jung, er ist auch schöner und stärker als "normale" Menschen. Doch die neue Wunderdroge hat einen Haken: Man braucht dazu das Blut von Menschen, deren DNA eine besondere Sequenz aufweist. Oft werden diese "Träger" entführt und in Blutfarmen gefangen gehalten.