• #Epi 123 - SWITCH Trial - Decompressive Craniectomy with Medical treatment Vs Best medical treatment for Deep intra-cerebral haemorrhage
    Jun 13 2024

    In this episode, we discuss the recently published SWITCH trial which compared the efficacy of decompressive craniectomy with best medical treatment vs best medical treatment alone for deep intra-cerebral hemorrhage.

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    26 mins
  • #Epi 122 - Diaphragmatic Dysfunction in Critically Ill patients
    Mar 16 2024

    In this episode, we discuss the etiology of diaphragmatic dysfunction, its management and strategies for prevention.

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    20 mins
  • # Epi 121 - AMIKINHAL Trial - Inhaled Amikacin to prevent Ventilator associated pneumonia
    Feb 27 2024

    In this episode, we discuss the recently published RCT AMIKINHAL, which tested the efficacy of inhaled amikacin in preventing VAP in ICU patients who were ventilated for> 72 hours. Although, this trail demonstrated reduced incidence of VAP in intervention arm, it's premature to adopt these practices widely in intensive care.

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    27 mins
  • #Epi 120 - NICO Trial - Intubation in Acute Drug Overdose - Does GCS matter?
    Dec 23 2023

    In this episode, we discuss recently published RCT in JAMA "NICO trial", which evaluated the role of GCS based intubation vs non-invasive airway management. It is important to understand the nuances before generalising the conclusion of this trial.

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    22 mins
  • #Epi 119 - The role of IV Thyroxine in Brain Dead Organ Donor
    Dec 17 2023

    In this episode, we discuss the recently published RCT in NEJM, which challenged the current dogma regarding the role of IV thyroxine in potential organ donor patient population.

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    18 mins
  • #Epi 118 - ECLS Shock Trial - Extra-corporeal support in Cardiogenic shock post-MI
    Oct 29 2023

    In this episode, we discuss the recently published RCT "ECLS-Shock" trial in NEJM. This trial tested the benefit of instituting early extra-corporeal support in cardiogenic shock and suggested more harm in intervention arm compared to control arm.

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    24 mins
  • #Epi 117 - ELAN Trial - Early Vs Late Anticoagulation in Ischaemic stroke post -AF
    Oct 4 2023

    In this episode, we discuss recently published landmark RCT which compared the timing for initiation of oral anticoagulation in patients who presented with ischaemic stroke with rapid AF.

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    25 mins
  • #Epi 116 - Steroids in Community Acquired Pneumonia
    Aug 21 2023

    In this episode, we discuss the controversy surrounding the usage of steroids in Community-acquired pneumonia. This controversy arose after the CAPE-COD trial was published recently in NEJM. We discuss the pros and cons of administering steroids as a blanket treatment. We recommend caution and suggest considering the external validity of this trial before changing your practices.

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    27 mins